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Structural characterisation of SNARE protein complexes involved in insulin-regulated glucose transport

Structural characterisation of SNARE protein complexes involved in insulin-regulated glucose transport
参与胰岛素调节葡萄糖转运的 SNARE 蛋白复合物的结构表征
批准号:
nhmrc : 569864
负责人:
Dr Andrew Whitten
金额:
$21.39万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31

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中文摘要
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英文摘要
Insulin-regulated glucose transportation is defective in type 2 diabetes, a disease that is a major health problem worldwide and in some cases can lead to death. The aim of this work is to investigate the molecular structure and function of proteins critical to the transportation and delivery of glucose to muscle and fat cells, which will lead to the validation of new therapeutic targets and the development of new treatments for diabetes.
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Molecular dissection of the Munc18c:Syntaxin4 complex required for insulin-regulated exocytosis in adipocytes
  • 批准号:
    nhmrc : 1066069
  • 项目类别:
    Project Grants
  • 资助金额:
    $40.08万
  • 财政年份:
    2014
  • 负责人:
    Dr Andrew Whitten
  • 依托单位:
海外基金