Systems pharmacology of antimicrobial drugs

抗菌药物的系统药理学

• 批准号: nhmrc : GNT1088855
• 负责人: Dr Darren Creek
• 金额: $ 41.18万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/systems-pharmacology-antimicrobial-drugs/1345754
• 关键词: Systems; pharmacology; antimicrobial; drugs

New medicines are urgently needed for infectious diseases due to widespread resistance to many traditional antibiotics. This research will develop and apply state-of-the-art techniques to measure metabolism in parasites and bacteria, and reveal how drugs inhibit metabolic pathways in these microorganisms. This will provide important information about how current drugs work, and assist with the development of new medicines for infectious diseases.

由于对许多传统抗生素的广泛耐药性，迫切需要治疗传染病的新药。这项研究将开发和应用最先进的技术来测量寄生虫和细菌的新陈代谢，并揭示药物如何抑制这些微生物的代谢途径。这将提供有关当前药物如何发挥作用的重要信息，并有助于开发治疗传染病的新药。