Targeting phosphoinositide metabolism in Leishmania

靶向利什曼原虫的磷酸肌醇代谢

• 批准号: nhmrc : GNT1138863
• 负责人: Prof Malcolm McConville
• 金额: $ 99.09万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-phosphoinositide-metabolism-leishmania/1348186
• 关键词: Targeting; phosphoinositide; metabolism; Leishmania

There is an urgent need to develop new drugs to treat human leishmaniasis, a disease that causes debilitating and life-threatening diseases in millions of people worldwide. This project will investigate whether it is possible to develop a new generation of drugs that target an important signaling pathway in these parasites that we have shown to be essential for virulence

目前迫切需要开发新的药物来治疗人类利什曼病，这是一种在全世界数百万人中导致衰弱和危及生命的疾病。这个项目将研究是否有可能开发新一代药物，靶向这些寄生虫中的一个重要信号通路，我们已经证明这是毒力所必需的