Neuregulins as modulators of dendritic growth and plasticity in the cerebral cortex

大脑皮层是一个复杂的网络，参与感觉、运动和认知信息的高级处理。有效的处理需要皮层神经元持续整合成千上万的皮层内和皮层外输入，这些输入主要存在于树突分支和棘上。树突是可以通过神经元活动形成的精细结构。在这里，我们建议研究如何生长因子称为neuregulins影响皮质树突的生长。这项研究将有助于我们了解脑回路的形态适应的生物学机制。

The cerebral cortex is a complex network involved in the high-level treatment of sensory, motor and cognitive information. Efficient processing requires cortical neurons to continuously integrate thousands of intra- and extra-cortical inputs, which are mostly found on dendritic branches and spines. Dendrites are elaborate structures which can be shaped by neuronal activity. Here, we propose to study how growth factors called neuregulins influence the growth of cortical dendrites. This study will contribute to our understanding of the biological mechanisms underlying morphological adaptations of brain circuitries.