Treating hyperglycaemia in diabetes with polyunsaturated fatty acid analogues

用多不饱和脂肪酸类似物治疗糖尿病高血糖症

• 批准号: nhmrc : 1011133
• 负责人: A/Pr Charles Hii
• 金额: $ 40.16万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/treating-hyperglycaemia-diabetes-acid-analogues/109551
• 关键词: Treating; hyperglycaemia; diabetes; polyunsaturated; fatty

Diabetes, characterised by elevated blood glucose, has a major impact on affected children, their families and the community. Our preliminary evidence suggests that a newly developed polyunsaturated fatty acid normalises blood glucose levels in an experimental diabetes model. This research will attempt to provide evidence that we have discovered a fat which has insulin like action and which may be taken orally once every 3-4 days to treat the elevated blood glucose.

以血糖升高为特征的糖尿病对受影响的儿童、其家庭和社区产生重大影响。我们的初步证据表明，一种新开发的多不饱和脂肪酸使实验性糖尿病模型的血糖水平正常化。这项研究将试图提供证据，证明我们已经发现了一种具有胰岛素样作用的脂肪，可以每3-4天口服一次来治疗血糖升高。