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Tuberous sclerosis and epilepsy: using resected tissue to understand pathogenesis and inform management

Tuberous sclerosis and epilepsy: using resected tissue to understand pathogenesis and inform management
结节性硬化症和癫痫:利用切除的组织了解发病机制并为治疗提供信息
批准号:
nhmrc : 1128933
负责人:
A/Pr Paul Lockhart
金额:
$23.1万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
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英文摘要
Epilepsy is the commonest neurological disorder in childhood and seizures cannot be fully controlled by medications in 30%, often leading to developmental consequences. A major cause of drug-resistant epilepsy is a malformation of the brain’s surface. Surgery is sometimes used to remove these lesions to treat the epilepsy. We will study this tissue to understand its architecture, genetic basis and how it causes seizures. Our results will guide treatment including the best surgical approach.
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Tuberous sclerosis and epilepsy: using resected tissue to understand pathogenesis and inform management
  • 批准号:
    nhmrc : GNT1128933
  • 项目类别:
    Project Grants
  • 资助金额:
    $33.93万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Paul Lockhart
  • 依托单位:
Understanding the Neurobiology of Autism Spectrum Disorder
  • 批准号:
    nhmrc : GNT1098255
  • 项目类别:
    Project Grants
  • 资助金额:
    $163.07万
  • 财政年份:
    2016
  • 负责人:
    A/Pr Paul Lockhart
  • 依托单位:
Understanding the Neurobiology of Autism Spectrum Disorder
  • 批准号:
    nhmrc : 1098255
  • 项目类别:
    Project Grants
  • 资助金额:
    $112.38万
  • 财政年份:
    2016
  • 负责人:
    A/Pr Paul Lockhart
  • 依托单位:
Determining the genetic control of Corpus Callosum development
  • 批准号:
    nhmrc : 1059666
  • 项目类别:
    Project Grants
  • 资助金额:
    $41.73万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Paul Lockhart
  • 依托单位:
国内基金
海外基金
小胶质细胞的IL-6/JAK/STAT3/MCP-1信号途径在MS/EAE发病过程中的作用
  • 批准号:
    81070958
  • 项目类别:
    面上项目
  • 资助金额:
    32.0万元
  • 批准年份:
    2010
  • 负责人:
    程琦
  • 依托单位: