Understanding uterine contractility: what can we learn from obesity?

了解子宫收缩力：我们可以从肥胖中学到什么？

• 批准号: nhmrc : 1042478
• 负责人: Prof Helena Parkington
• 金额: $ 40.06万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-uterine-contractility-learn-obesity/111472
• 关键词: Understanding; uterine; contractility; what; learn

The incidence of failure to progress in labour has increased in recent years, being linked to the rise in obesity. The result is a significant escalation in the rate of delivery by Caesarean Section (CS) which increases the risk of serious complications during subsequent pregnancies. We have identified five dysfunctional systems associated with poor uterine contraction. We now aim to determine the mechanisms underlying these dysfunctional systems, particularly those mechanisms in common.

近年来，分娩失败的发生率有所增加，这与肥胖症的增加有关。其结果是剖腹产(CS)的分娩率显著上升，这增加了在随后怀孕期间发生严重并发症的风险。我们已经确定了五个与子宫收缩不良相关的功能失调系统。我们现在的目标是确定这些功能失调系统背后的机制，特别是那些共同的机制。