The unholy alliance between extracorporeal circuitry and transfusion medicine: characterising inflammation and injury

体外回路与输血医学之间的邪恶联盟：炎症和损伤的特征

• 批准号: nhmrc : 1010939
• 负责人: A/Pr Andreas Schibler
• 金额: $ 63.6万
• 依托单位: Prince Charles Hospital
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/unholy-alliance-extracorporeal-inflammation-injury/109540
• 关键词: unholy; alliance; between; extracorporeal; circuitry

Extra Corporeal Membrane Oxygenation (ECMO) is a heart/lung machine that replaces blood CO2 with oxygen, giving organs a chance to rest after injury due to infection or trauma. It saved many lives in the swine flu outbreak. Blood moving across foreign surfaces causes inflammation, cell injury and a need for transfusions. This study aims to identify which part of the ECMO causes injury and how. This will to improve survival rates of the most severe forms of cardiac and respiratory disease.

ECMO是一种心肺机，用氧气代替血液中的CO2，使器官在感染或创伤后有机会休息。它在猪流感爆发时挽救了许多人的生命。血液流过异物表面会导致炎症、细胞损伤和输血。这项研究旨在确定ECMO的哪个部分会导致损伤以及如何导致损伤。这将提高最严重的心脏和呼吸系统疾病的存活率。