Hyperpolarized Helium MRI to quantify regional lung damage and ventilation for improvement of recruitment strategy.

超极化氦 MRI 可量化局部肺损伤和通气，以改进肺复张策略。

• 批准号: nhmrc : 519716
• 负责人: A/Pr Andreas Schibler
• 金额: $ 30.35万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/hyperpolarized-helium-mri-recruitment-strategy/76534
• 关键词: Hyperpolarized; Helium; MRI; quantify; regional

Many lung injuries need mechanical ventilation to reopen collapsed lung airspaces and supply oxygen to the patient. This study uses two methods to monitor the lungs during ventilation: Hyperpolarised helium MRI to image the airspace, and electrical impedance tomography to measure lung volume. This information will allow adjustment of ventilator pressure to maximize oxygen transfer without increasing lung damage. Quicker repair of lung damage and patient recovery are the benefits of this study.

许多肺损伤需要机械通气来重新打开塌陷的肺空间并向患者提供氧气。本研究使用两种方法在通气期间监测肺部：超极化氦MRI对空域进行成像，电阻抗断层扫描测量肺容量。该信息将允许调整呼吸机压力，以在不增加肺损伤的情况下最大化氧气输送。肺损伤的更快修复和患者恢复是本研究的益处。