Nitric Oxide on Cardio Pulmonary Bypass in Congenital Heart Disease

一氧化氮在先天性心脏病心肺转流术中的作用

• 批准号: nhmrc : 1140322
• 负责人: A/Pr Andreas Schibler
• 金额: $ 127.04万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/nitric-oxide-cardio-heart-disease/1319221
• 关键词: Nitric; Oxide; Cardio; Pulmonary; Bypass

Children undergoing open heart surgery on a heart lung machine can experience serious side effects from the exposure to the artificial circulation during surgery and may have either prolonged need for life support in intensive care or even may suffer from long term complications. In this study we investigate the use of a new approach using nitric oxide, a anti-inflammatory gas, during surgery to reduce these side effects.

在心肺机上接受心脏直视手术的儿童可能会因手术过程中暴露于人工循环而出现严重的副作用，并且可能需要在重症监护室长期维持生命，甚至可能出现长期并发症。在这项研究中，我们研究了一种新的方法，在手术过程中使用一氧化氮，一种抗炎气体，以减少这些副作用。