Use of a new, highly sensitive approach to discover new human genes and elements involved in disease.

使用高度敏感的新方法来发现与疾病有关的新人类基因和元素。

• 批准号: nhmrc : GNT1062470
• 负责人: A/Pr Timothy Mercer
• 金额: $ 40.49万
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/use-new-highly-involved-disease/1344807
• 关键词: Use; new; highly; sensitive; approach

Dr. Mercer will develop a new technology, CaptureSeq that is able to focus RNA sequencing on targeted regions of interest. This focus gives CaptureSeq an unprecedented sensitivity to discover new genes and regulatory elements in regions of the genome that have been associated with disease but are otherwise barren and empty. This project will thereby uncover both new genes candidates for further disease research and develop a technology with unique and widespread research and clinical potential.

美世博士将开发一种新技术，CaptureSeq，能够将RNA测序集中在目标区域。这一关注使CaptureSeq具有前所未有的灵敏度，可以在与疾病相关但其他方面贫瘠和空白的基因组区域中发现新的基因和调控元件。因此，该项目将发现新的候选基因，以进一步研究疾病，并开发具有独特和广泛研究和临床潜力的技术。