A high-pressure liquid chromatography instrument
A high-pressure liquid chromatography instrument
批准号:
390364-2010
负责人:
Gleason, James
金额:
$4.97万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-01-01 至 2010-12-31
中文摘要
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英文摘要
Our research group has developed a large research thrust in the area of hybrid drug development. These molecules combine inhibitory activity for the histone deacetylase inhibitor with either agonism or antagonism for nuclear receptors (vitamin D, estrogen and retinoic acid receptors) and represent exciting new potential therapies for cancer and tuberculosis. A key to the analysis of these new molecules is having analytically pure samples for testing both against cells in culture and in animal xenografts. We urgently require a high-pressure liquid chromatography instrument for purification of our hybrid molecules so that we can continue and expand this important research project.
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会议论文
Development and application of cyclic hydrazides as organocatalysts
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批准号:RGPIN-2018-06461
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.99万
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财政年份:2022
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负责人:Gleason, James
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依托单位:
Development and application of cyclic hydrazides as organocatalysts
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批准号:RGPIN-2018-06461
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2021
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负责人:Gleason, James
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依托单位:
Development and application of cyclic hydrazides as organocatalysts
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批准号:RGPIN-2018-06461
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2020
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负责人:Gleason, James
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依托单位:
Development and application of cyclic hydrazides as organocatalysts
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批准号:RGPIN-2018-06461
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2019
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负责人:Gleason, James
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依托单位:
Development and application of cyclic hydrazides as organocatalysts
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批准号:RGPIN-2018-06461
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2018
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负责人:Gleason, James
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依托单位:
Studies in Natural Product Synthesis and Catalysis of Pericyclic Reactions
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批准号:194399-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2017
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负责人:Gleason, James
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依托单位:
Development of General Approach to Substituted Bicylo[1.1.1]pentanes
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批准号:507659-2016
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项目类别:Engage Grants Program
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资助金额:$1.82万
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财政年份:2016
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负责人:Gleason, James
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依托单位:
Studies in Natural Product Synthesis and Catalysis of Pericyclic Reactions
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批准号:194399-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2016
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负责人:Gleason, James
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依托单位:
Studies in Natural Product Synthesis and Catalysis of Pericyclic Reactions
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批准号:194399-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2015
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负责人:Gleason, James
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依托单位:
Studies in Natural Product Synthesis and Catalysis of Pericyclic Reactions
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批准号:194399-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2014
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负责人:Gleason, James
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依托单位:
Studies in Natural Product Synthesis and Catalysis of Pericyclic Reactions
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批准号:194399-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2013
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负责人:Gleason, James
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依托单位:
Asymmetic synthesis and applications of cycloadditions to complex natural products synthesis
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批准号:194399-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.15万
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财政年份:2012
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负责人:Gleason, James
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依托单位:
Asymmetic synthesis and applications of cycloadditions to complex natural products synthesis
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批准号:194399-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.15万
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财政年份:2011
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负责人:Gleason, James
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依托单位:
Asymmetic synthesis and applications of cycloadditions to complex natural products synthesis
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批准号:194399-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.15万
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财政年份:2010
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负责人:Gleason, James
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依托单位:
Asymmetic synthesis and applications of cycloadditions to complex natural products synthesis
-
批准号:194399-2008
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项目类别:Discovery Grants Program - Individual
-
资助金额:$4.15万
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财政年份:2009
-
负责人:Gleason, James
-
依托单位:
Asymmetic synthesis and applications of cycloadditions to complex natural products synthesis
-
批准号:194399-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.15万
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财政年份:2008
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负责人:Gleason, James
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依托单位:
New methods in synthesis
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批准号:194399-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.79万
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财政年份:2006
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负责人:Gleason, James
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依托单位:
New methods in synthesis
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批准号:194399-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.79万
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财政年份:2005
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负责人:Gleason, James
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依托单位:
Dynamic combinatorial chemistry applied to the identification of vitamin D analogs for cancer therapy
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批准号:262528-2003
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项目类别:Collaborative Health Research Projects
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资助金额:$9.12万
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财政年份:2005
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负责人:Gleason, James
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依托单位:
New methods in synthesis
-
批准号:194399-2003
-
项目类别:Discovery Grants Program - Individual
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资助金额:$3.79万
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财政年份:2004
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负责人:Gleason, James
-
依托单位:
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