Controlled release of active compounds from nanocapsule polymers

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The use of nanocapsules and nanoparticles in the delivery of active compounds (AIs) in agriculture and biomedical applications has been actively pursued. However, the quantification of the release of AIs has been problematic due to the size of these nanoparticles. In order to measure the concentration of AI released from the nanoparticles, the AI loaded nanoparticles have to be separated from the bulk solution. Two common techniques are used, namely centrifugation and filtration, but they present numerous problems, such as forced release of AI, adsorption on filters, and blockage of pores. Thus, an alternative method that is more reliable and accurate needs to be developed to facilitate such measurements. Recently, Tam and co-workers have demonstrated that the Electromotive Force (EMF) measurements can be readily used to perform such measurements. They have demonstrated that the proposed method is accurate and simple to implement. The