Utilizing Biomaterials to Improve the Differentiation & Integration of Human Stem Cell-Derived Neural Grafts in Parkinson’s Disease
Utilizing Biomaterials to Improve the Differentiation & Integration of Human Stem Cell-Derived Neural Grafts in Parkinson’s Disease
利用生物材料提高分化能力
批准号：
nhmrc : GNT1159265
负责人：
金额：
$80.65万
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2019
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2019-01-01 至 --
中文摘要
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英文摘要
Clinical trials have shown that transplanting dopamine neurons into the brain of Parkinson's disease patients can improve symptoms. Trials used fetal tissue for implantation, which is unsustainable and highly variable. This proposal will examine human stem cells as an alternative donor source and employ our carefully engineered scaffolds to support these stem cells prior to, and following, transplantation into models of the disease.
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