Validating a potential therapeutic for amyotrophic lateral sclerosis

验证肌萎缩侧索硬化症的潜在治疗方法

• 批准号: nhmrc : 1005651
• 负责人: A/Pr Paul Donnelly
• 金额: $ 40.96万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/validating-potential-therapeutic-lateral-sclerosis/109101
• 关键词: Validating; potential; therapeutic; amyotrophic; lateral

ALS is a form of motor neuron disease that quickly renders people paralysed by killing off the nerves needed for muscle control. It affects people when they are 40-60 years old, and very few survive more than 5 years after diagnosis. Our team is testing a new therapeutic compound that we have already shown to delay paralysis in mice with ALS. The work we are currently undertaking will provide all the necessary information required before we are able to test our compound in people with ALS.

ALS是一种运动神经元疾病，通过杀死肌肉控制所需的神经，迅速使人瘫痪。它影响40-60岁的人，很少有人在诊断后存活超过5年。我们的团队正在测试一种新的治疗化合物，我们已经证明它可以延缓ALS小鼠的瘫痪。我们目前正在进行的工作将提供在我们能够在ALS患者中测试我们的化合物之前所需的所有必要信息。