New ligands, reagents and strategies for asymmetric synthesis

不对称合成的新配体、试剂和策略

• 批准号: 93010-2007
• 负责人: Chong, Michael
• 金额: $ 4.41万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=451210
• 关键词: New; ligands; reagents; strategies; asymmetric

The proposed research is aimed at developing new methods for the synthesis of chiral compounds. Since the chirality or handedness of a drug can have a major impact on its biological activity, it is important to make potential drugs either entirely left-handed or right-handed. The focus will be on creating new reagents to carry out transformations which are not currently possible using existing methodology or have significant advantages over existing methodology.

该研究旨在开发新的手性化合物合成方法。 由于药物的手性或手性对其生物活性有重大影响，因此使潜在的药物完全左手或右手是很重要的。 重点将是创造新的试剂，以进行目前使用现有方法不可能实现的转化，或比现有方法具有显着优势。