New ligands, reagents and strategies for asymmetric synthesis

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The proposed research is aimed at developing new methods for the synthesis of chiral compounds. Since the chirality or handedness of a drug can have a major impact on its biological activity, it is important to make potential drugs either entirely left-handed or right-handed. The focus will be on creating new reagents to carry out transformations which are not currently possible using existing methodology or have significant advantages over existing methodology.