Virtuous cycles: a novel cyclic peptide approach to develop neuroprotective and cardioprotective drugs

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Each year, 110,000 Australian have a stroke or heart attack, and 20,000 die as a result. Stroke and heart attack are ischemic injuries caused by reduced blood flow to the affected organ. Clot-busting drugs can be used to restore blood flow but they do not address the underlying tissue damage caused by the ischemic insult. We aim to develop a drug that protects the brain and heart after stroke and heart attack, respectively. This drug will save lives and improve quality-of-life for survivors.