Virus vaccines that ensure preparedness against future public health emergencies

确保为未来突发公共卫生事件做好准备的病毒疫苗

• 批准号: nhmrc : GNT1144025
• 负责人: Dr Daniel Watterson
• 金额: $ 86.21万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/virus-vaccines-ensure-health-emergencies/1348576
• 关键词: Virus; vaccines; ensure; preparedness; against

In this proposal, we will utilize novel technology we have developed (the molecular clamp) to generate candidate subunit vaccines and therapeutic antibody treatments against four highly pathogenic viruses identified by the World Health Organization as requiring urgent R&D to prepare for future epidemics; Ebola virus, Middle East Respiratory Coronavirus, Nipah virus and Lassa fever virus. Resulting vaccines are expected to provide advantages including safety, efficacy, and thermal stability.

在这项建议中，我们将利用我们开发的新技术(分子钳)来生产候选亚单位疫苗和治疗性抗体疗法，以对抗世界卫生组织确定的四种高致病性病毒，即埃博拉病毒、中东呼吸道冠状病毒、尼帕病毒和拉沙热病毒，这些病毒需要紧急研发，为未来的流行做准备。由此产生的疫苗有望提供包括安全性、有效性和热稳定性在内的优势。