Can vitamin D prevent diabetes by improving insulin sensitivity and secreation in overweight humans?

维生素 D 能否通过改善超重人群的胰岛素敏感性和分泌来预防糖尿病？

• 批准号: nhmrc : 1047897
• 负责人: A/Pr Barbora De Courten
• 金额: $ 47.7万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/vitamin-d-prevent-overweight-humans/111976
• 关键词: vitamin; prevent; diabetes; improving; insulin

Vitamin D is mainly produced by the action of sunlight on skin. Low levels of vitamin D are becoming more common, as we work more indoors and avoid the sun and have been associated with type 2 diabetes. In proposed study, healthy overweight people, with low vitamin D, will be given vitamin D for 16 weeks to optimise blood levels of this vitamin. We will examine the changes in sugar metabolism. This study should provide important evidence on how vitamin D protects against diabetes and will support novel approaches to diabetes prevention.

维生素D主要是通过阳光照射皮肤产生的。低水平的维生素D变得越来越普遍，因为我们更多地在室内工作，避免阳光照射，并与2型糖尿病有关。在拟议的研究中，健康超重的人，低维生素D，将给予维生素D 16周，以优化这种维生素的血液水平。我们将研究糖代谢的变化。这项研究应该为维生素D如何预防糖尿病提供重要证据，并将支持预防糖尿病的新方法。