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surface bioconjugaison for regenerative medicine applications

surface bioconjugaison for regenerative medicine applications
用于再生医学应用的表面生物共轭
批准号:
314056-2010
负责人:
DeCrescenzo, Gregory
金额:
$3.93万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-01-01 至 2011-12-31

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中文摘要
翻译
再生医学的一个主要挑战在于精确和有效地控制细胞和材料之间的相互作用。在过去的十年里,有潜力作为支架来支持细胞生长的新材料的开发经历了快速的扩张。在此背景下,旨在取代小直径动脉的新型血管疗法现在被开发用于治疗疾病血管,疾病血管是加拿大疾病、残疾和死亡的主要原因。然而,目前的问题包括假体内皮化的缺乏,这受到组成移植物的生物材料的固有特性的限制,并与移植物血栓形成和内膜增生的高发生率直接相关。
英文摘要
One main challenge in regenerative medicine resides in the precise and efficient control of the interactions between cells and materials. Within the last decade, the development of new materials with potential to serve as scaffolds to support cell growth has undergone rapid expansion. In that context, novel vascular therapies aiming at replacing small diameter arteries are now developed to treat diseased vessels, the major cause of illness, disability and death in Canada. However, current issues include the lack of prosthetic endothelialization that is limited by the intrinsic properties of the biomaterial composing the grafts, and directly related to high occurrence of graft thrombosis and intimal hyperplasia.
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  • 批准号:
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  • 项目类别:
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  • 资助金额:
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  • 项目类别:
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