Development and evaluation of novel bone anchors and "smart" adaptive implants for the treatment of the bone deficient skeleton

用于治疗骨缺损骨骼的新型骨锚和“智能”自适应植入物的开发和评估

• 批准号: 342890-2007
• 负责人: Frei, Hanspeter
• 金额: $ 1.35万
• 依托单位: Carleton University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=458836
• 关键词: Development; evaluation; novel; bone; anchors

Loss of the biomechanical integrity of the skeleton due to fracture or loss of bone tissue often leads to premature disability and leaves the patient with a reduced quality of life. The economic burden on the health care system of skeletal conditions such as osteoporosis-related fractures, osteolytic bone loss and other bone defects related to trauma, bone tumors and surgical resections is enormous. Despite considerable research efforts in implant design, augmentation methods and regenerative medicine approaches, the surgical treatment of the bone deficient skeleton remains challenging with unsatisfactionary clinical outcomes.

由于骨折或骨组织损失导致的骨骼生物力学完整性的损失通常导致过早残疾，并使患者生活质量降低。骨骼疾病，如骨质疏松相关的骨折、溶骨性骨丢失和其他与创伤、骨肿瘤和手术切除相关的骨缺损，给卫生保健系统带来了巨大的经济负担。尽管在种植体设计、增强方法和再生医学方法方面进行了大量的研究，但骨缺损骨骼的手术治疗仍然具有挑战性，临床结局不令人满意。