Genome Approaches to Investigate Metabolic Coordination in Plant Cells

研究植物细胞代谢协调的基因组方法

• 批准号: ARC : DP0343517
• 负责人: Penelope Smith
• 金额: $ 36万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genome-approaches-investigate-plant-cells/67332
• 关键词: Genome; Approaches; Investigate; Metabolic; Coordination

Genome Approaches to Investigate Metabolic Coordination in Plant Cells. Metabolism of C and N in legume nodules requires interaction between the symbiotic bacteria and plant organelles, particularly metabolism in plastids and mitochondria. Fixed N is assimilated through the de novo synthesis of purines in both plastids and mitochondria. However, each of the nine pathway enzymes is encoded by a single gene, indicating each protein is targeted to both organelles. Purine metabolism will provide a model to assess the more general occurrence of dual-targeted proteins in plants. The aim is to identify and eventually exploit the signalling mechanism(s) that mediate communication between plastids and mitochondria.

研究植物细胞代谢协调的基因组方法。豆科植物根瘤中碳、氮的代谢需要共生细菌与植物细胞器之间的相互作用，特别是在叶绿体和线粒体中的代谢。固定氮是通过质体内和线粒体中的嘌呤从头合成而被吸收的。然而，九种途径的酶中的每一种都由单个基因编码，这表明每种蛋白质都针对两个细胞器。嘌呤代谢将提供一个模型来评估植物中更普遍的双靶标蛋白的出现情况。其目的是识别并最终利用介导叶绿体和线粒体之间通讯的信号机制(S)。