Implementation of genomic selection in Canadian coloured dairy breeds

在加拿大有色奶牛品种中实施基因组选择

• 批准号: 391351-2009
• 负责人: Schenkel, Flavio
• 金额: $ 3.42万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=464751
• 关键词: Implementation; genomic; selection; Canadian; coloured

Genomic selection involves the use of dense marker maps of the genome and the application of statistical models to simultaneously estimate the effects of small chromosome segments linked to the markers, The estimates can be used to evaluate the genetic merit of an animal through agenomic estimated breeding value. Genomic selection methods have been developed and implemented in Canada for Holstein cattle in a collaboration effort between Canadian and American researchers. The proposal is to extend the work carried out for Holsteins by developing and implementing genomic selection in coloured dairy breeds in Canada. The proposed study includes the development of aresource population of genotyped animals for estimating marker effects. the determination of the appropriate set of marker to be used for each breed and implementation of specific methods for each breed when needed. Validation studies will be carried out to assess the gains in

基因组选择包括使用基因组的密集标记图和应用统计模型来同时估计与标记相关的小染色体片段的影响，这些估计值可用于通过基因组估计育种价值来评估动物的遗传优点。在加拿大和美国研究人员的合作下，加拿大已经开发并实施了荷斯坦牛的基因组选择方法。该提案是通过在加拿大开发和实施彩色奶牛品种的基因组选择来扩展为荷斯坦奶牛开展的工作。建议的研究包括开发基因型动物的资源种群，以估计标记效应。为每个品种确定合适的标记，并在需要时为每个品种实施特定的方法。将进行验证研究，以评估在