Development of funtional peptide nanostructures

功能性肽纳米结构的开发

• 批准号: 197473-2007
• 负责人: Voyer, Normand
• 金额: $ 3.64万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=476784
• 关键词: Development; funtional; peptide; nanostructures

This proposal described a multidisciplinary research program that aims at developing novel compounds of nanometer size to be used in highly sensitive diagnostic devices, smart drug delivery systems and, eventually, in clinic to combat cancers resistant to actual chemotherapeutic agents. The design of the nanoscale compounds is inspired by natural biological systems. More specifically, we exploit polypeptides as basic material to construct our artificial compounds, the same material used by living cells to create outstanding biomolecular systems to carry out all the necessary biomolecular processses required for cell survival and replication.

该提案描述了一个多学科研究项目，旨在开发纳米尺寸的新型化合物，用于高灵敏度的诊断设备、智能药物输送系统，并最终用于临床，以对抗对实际化疗药物产生耐药性的癌症。纳米级化合物的设计灵感来自于自然生物系统。更具体地说，我们利用多肽作为构建人工化合物的基本材料，活细胞使用相同的材料来创建出色的生物分子系统，以执行细胞生存和复制所需的所有必要的生物分子过程。