Structural characterization of proteins involved in iron uptake in C. jejuni

空肠弯曲菌铁摄取相关蛋白质的结构表征

• 批准号: 203456-2008
• 负责人: Baenziger, John
• 金额: $ 2.5万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=477133
• 关键词: Structural; characterization; proteins; involved; iron

Many food borne illnesses are caused by the pathogenic bacterium, Campylobacter jejuni. In humans, infection with this organism can lead to severe abdominal cramping, headache, diarrhea and in extreme cases death. C. jejuni infects 1% of the United States population annually. Some of those affected can also develop an autoimmune disorder of the peripheral nervous system that results in weakening of muscles and, in some cases, neurological problems.

许多食源性疾病是由致病细菌空肠弯曲杆菌引起的。在人类中，感染这种细菌可能会导致严重的腹部痉挛、头痛、腹泻，在极端情况下还会死亡。空肠弯曲菌每年感染1%的美国人口。一些受影响的人还会发展成周围神经系统的自身免疫性疾病，导致肌肉虚弱，在某些情况下，还会出现神经问题。