The cellular basis of temperature impairment of reproductive function in Atlantic salmon

温度损害大西洋鲑鱼生殖功能的细胞基础。夏季和秋季气温升高，无论是由于正常的气候变化还是全球变暖，都通过扰乱内分泌（激素过程）来抑制鲑科鱼类的繁殖。所涉及的机制尚不清楚，但已知与抑制卵巢雌激素和蛋黄蛋白的组装有关。本项目将在卵巢和肝脏水平上研究高温对生殖抑制作用的细胞基础。所形成的理解将是在变暖的环境条件下管理鲑鱼和鳟鱼继续成功养殖的改进战略的重要组成部分。

The cellular basis of temperature impairment of reproductive function in Atlantic salmon. Elevated summer and autumn temperatures, either as a result of normal climate variation or global warming, inhibit reproduction in salmonid fishes by disrupting endocrine (hormonal processes). The mechanisms involved are unclear but are known to involve inhibition of ovarian estrogen and the assembly of egg-yolk proteins. This project will investigate the cellular basis of the inhibitory effect of high temperature on reproduction, at the ovarian and hepatic levels. The understanding developed will be an essential component of amelioration strategies for managing the continued successful rearing of salmon and trout under warming environmental conditions.