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Involvement of intracellular phosphoinositides in the regulation of neuronal and glial P2X receptors implicated in pain pathologies.

Involvement of intracellular phosphoinositides in the regulation of neuronal and glial P2X receptors implicated in pain pathologies.
细胞内磷酸肌醇参与调节与疼痛病理有关的神经元和神经胶质 P2X 受体。
批准号:
184504
负责人:
Bernier Louis-Philippe
金额:
$7.65万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-10-01 至 2011-10-01

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中文摘要
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英文摘要
P2X receptors are ATP-gated non-selective cation channels highly permeable to calcium that contribute to nociception and inflammatory responses. This project will focus on the intracellular regulatory pathways of three P2X subtypes: P2X2/3, P2X3 and P2X4
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会议论文
Characterization of the acute morphological and functional response of microglia to decreased oxygen levels and study of the mechanisms underlying microglial dynamic motility.
  • 批准号:
    296963
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $10.2万
  • 财政年份:
    2013
  • 负责人:
    Bernier Louis-Philippe
  • 依托单位:
Characterization of the acute morphological and functional response of microglia to decreased oxygen levels and study of the mechanisms underlying microglial dynamic motility.
  • 批准号:
    300751
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $9.83万
  • 财政年份:
    2013
  • 负责人:
    Bernier Louis-Philippe
  • 依托单位:
Intracellular regulation of P2X4 receptors by phosphoinositides via P2Y activation
  • 批准号:
    187947
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $0.44万
  • 财政年份:
    2009
  • 负责人:
    Bernier Louis-Philippe
  • 依托单位:
海外基金