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Molecular aging: Mouse molecular models for Werner syndrome.

Molecular aging: Mouse molecular models for Werner syndrome.
分子衰老:维尔纳综合征的小鼠分子模型。
批准号:
237542
负责人:
Lebel Michel
金额:
$55.42万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2016-09-01

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中文摘要
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英文摘要
One of the most fascinating of human aging syndromes is Werner syndrome (WS). WS is a recessive disorder characterized by genomic instability and the premature onset of several age-related diseases. The precise function of the WS protein (WRN) in genomic
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Oxidative stress in the endoplasmic reticulum and its impact on liver inflammation in an aging mouse model
Identification of microRNAs important for the lifespan of animal models for the premature aging Werner syndrome.
  • 批准号:
    228759
  • 项目类别:
    Operating Grants
  • 资助金额:
    $3.64万
  • 财政年份:
    2010
  • 负责人:
    Lebel Michel
  • 依托单位:
Understanding the molecular role of the Werner syndrome gene product in preventing aging disorders in the general population.
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