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Functional genomics of cilium formation and maintenance

Functional genomics of cilium formation and maintenance
纤毛形成和维持的功能基因组学
批准号:
252623
负责人:
Leroux Michel R
金额:
$45.31万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2017-03-01

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英文摘要
Cilia are antenna-like cellular structures used for numerous physiological and developmental processes. In humans, motile cilia perform critical functions, such as clearing debris from respiratory systems or allowing sperm movement. Non-motile (sensory) c
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Regulation of the intraflagellar transport pathway, a mutational hotspot required for cilium formation and maintenance
Cell biology of an evolutionarily conserved ciliary compartment essential for cellular signalling
Dissecting the molecular and cellular links between cilia, cGMP signaling, physiology and disease
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