Regulation of the intraflagellar transport pathway, a mutational hotspot required for cilium formation and maintenance
Regulation of the intraflagellar transport pathway, a mutational hotspot required for cilium formation and maintenance
批准号:
371335
负责人:
Leroux Michel R
金额:
$54.34万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01
中文摘要
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英文摘要
Cilia, the antenna-shaped structures found on most human cells, have recently emerged as major hotspots for genetic diseases called ciliopathies. Over 30 different ciliopathies, caused by mutations in nearly 200 genes, are currently known. Defects in the
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Cell biology of an evolutionarily conserved ciliary compartment essential for cellular signalling
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批准号:321731
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项目类别:Operating Grants
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资助金额:$50.27万
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财政年份:2015
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负责人:Leroux Michel R
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依托单位:
Functional genomics of cilium formation and maintenance
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批准号:252623
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项目类别:Operating Grants
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资助金额:$45.31万
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财政年份:2012
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负责人:Leroux Michel R
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依托单位:
Dissecting the molecular and cellular links between cilia, cGMP signaling, physiology and disease
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批准号:181166
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项目类别:Operating Grants
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资助金额:$39.08万
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财政年份:2009
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负责人:Leroux Michel R
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依托单位:
海外基金