Novel regulatory features of eukaryotic ribosomal proteins

真核核糖体蛋白的新调控特征

• 批准号: 253165
• 负责人: Bachand Francois
• 金额: $ 50.18万
• 依托单位: Centre hospitalier universitaire de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253165&lang=en
• 关键词: Culture Human Cells; Extra-Ribosomal Functions; Fission Yeast; Gene Regulation; Genomics; Nuclear Rna Surveillance; Proteomics; Ribosomal Proteins; Splicing; Yeast Genetics

Ribosomal proteins (RPs) are abundant RNA-binding proteins that normally function in the folding of ribosomal RNA molecules to allow the formation of the ribosome, the molecular machine responsible for protein synthesis. Surprisingly, however, mutations i

核糖体蛋白（RP）是丰富的RNA结合蛋白，其通常在核糖体RNA分子的折叠中起作用，以允许核糖体的形成，核糖体是负责蛋白质合成的分子机器。然而，令人惊讶的是，