Deciphering cellular mechanisms regulating neuromuscular development
Deciphering cellular mechanisms regulating neuromuscular development
批准号:
238826-2012
负责人:
Rafuse, Victor
金额:
$3.5万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-01-01 至 2013-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Motoneurons innervate their appropriate muscle targets with remarkable precision during embryogenesis. To accomplish this task, the growth cone must make numerous pathfinding decisions as it grows to its correct target. Most decisions can be described as growing towards a desired guidance cue or away from a repulsive one. A directional decision shared by all developing motor axons is that to extend an axon out of the spinal cord. The last decision is more refined and involves determining whether to synapse with a fast or slow contracting muscle fibre. Ultimately, all guidance cues activate distinct intracellular signaling pathways that trigger asymmetrical changes in the growth cone causing it to turn towards or away from a cue.
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会议论文
Stem Cell Derived Motoneurons to study motor neuron development
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批准号:RGPIN-2020-06730
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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依托单位:
Stem Cell Derived Motoneurons to study motor neuron development
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2021
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依托单位:
Stem Cell Derived Motoneurons to study motor neuron development
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批准号:RGPIN-2020-06730
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2020
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负责人:Rafuse, Victor
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Deciphering cellular mechanisms regulating neuromuscular development
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批准号:238826-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2019
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依托单位:
Deciphering cellular mechanisms regulating neuromuscular development
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批准号:238826-2012
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资助金额:$3.5万
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依托单位:
Deciphering cellular mechanisms regulating neuromuscular development
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批准号:238826-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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负责人:Rafuse, Victor
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Deciphering cellular mechanisms regulating neuromuscular development
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批准号:238826-2012
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资助金额:$3.5万
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依托单位:
Deciphering cellular mechanisms regulating neuromuscular development
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批准号:238826-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2015
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负责人:Rafuse, Victor
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依托单位:
Deciphering cellular mechanisms regulating neuromuscular development
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批准号:238826-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2014
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负责人:Rafuse, Victor
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依托单位:
Deciphering cellular mechanisms regulating neuromuscular development
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批准号:238826-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2013
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating the differentiation of embryonic stem cells into functional motoneurons
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批准号:238826-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.99万
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating the differentiation of embryonic stem cells into functional motoneurons
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批准号:238826-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.99万
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财政年份:2010
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating the differentiation of embryonic stem cells into functional motoneurons
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批准号:238826-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.99万
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财政年份:2009
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating the differentiation of embryonic stem cells into functional motoneurons
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批准号:238826-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.99万
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财政年份:2008
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating the differentiation of embryonic stem cells into functional motoneurons
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批准号:238826-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.99万
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财政年份:2007
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating neural stem cell differentiation and growth in the developing chick spinal cord
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批准号:238826-2002
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.92万
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财政年份:2006
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating neural stem cell differentiation and growth in the developing chick spinal cord
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批准号:238826-2002
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.92万
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财政年份:2005
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating neural stem cell differentiation and growth in the developing chick spinal cord
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批准号:238826-2002
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.92万
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财政年份:2004
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负责人:Rafuse, Victor
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依托单位:
Characterization of the mechanisms regulating neural stem cell differentiation and growth in the developing chick spinal cord
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批准号:238826-2002
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.92万
-
财政年份:2003
-
负责人:Rafuse, Victor
-
依托单位:
Characterization of the mechanisms regulating neural stem cell differentiation and growth in the developing chick spinal cord
-
批准号:238826-2002
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.92万
-
财政年份:2002
-
负责人:Rafuse, Victor
-
依托单位:
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