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Familial hypertrophic cardiomyopathy: etiology involving troponin mutations

Familial hypertrophic cardiomyopathy: etiology involving troponin mutations
家族性肥厚型心肌病：涉及肌钙蛋白突变的病因
批准号：
266065
负责人：
Tibbits Glen F
金额：
$33.01万
依托单位：
Simon Fraser University (Burnaby, B.C.)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-09-01 至 2015-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=266065&lang=en
关键词：
Ca Handling Cardiomyocyte Crystal Structure Of Troponin Complex Isothermal Calorimetry (Itc) Molecular Dynamic Simulation Molecular Dynamic Simulations Myofilament Calcium Sensitivity Nmr Structure Of Troponin C Troponin C

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中文摘要
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英文摘要
Familial hypertrophy cardiomyopathy (FHC) is a congenital heart disease which causes the walls of the heart to thicken (hypertrophy) and disrupts the organization of the heart's contractile machinery. Even though numerous genetic defects (mutations) have
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Using hiPSC-derived atrial tissue to understand better the role of SK ion channel variants in atrial fibrillation
Mechanisms by which thin filament variants induce hypertrophic cardiomyopathy
Catecholaminergic polymorphic ventricular tachycardia (CPVT): arrhythmogenic mechanisms and personalized intervention
  • 批准号：
    433403
  • 项目类别：
    Operating Grants
  • 资助金额：
    $67.32万
  • 财政年份：
    2020
  • 负责人：
    Tibbits Glen F
  • 依托单位：
    University of British Columbia
Arrhythmogenic mutations in the neonate cardiac contractile element
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