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Mechanisms by which thin filament variants induce hypertrophic cardiomyopathy

Mechanisms by which thin filament variants induce hypertrophic cardiomyopathy
细丝变异诱发肥厚性心肌病的机制
批准号:
470627
负责人:
Tibbits Glen F
金额:
$78.86万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01

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中文摘要
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英文摘要
Hypertrophy cardiomyopathy (HCM) is a congenital heart disease that causes the walls of the heart to thicken (hypertrophy) and disrupts the organization of the heart's contractile machinery. Even though numerous genetic defects (variants) have been associ
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Using hiPSC-derived atrial tissue to understand better the role of SK ion channel variants in atrial fibrillation
Catecholaminergic polymorphic ventricular tachycardia (CPVT): arrhythmogenic mechanisms and personalized intervention
  • 批准号:
    433403
  • 项目类别:
    Operating Grants
  • 资助金额:
    $67.32万
  • 财政年份:
    2020
  • 负责人:
    Tibbits Glen F
  • 依托单位:
Arrhythmogenic mutations in the neonate cardiac contractile element
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