Discovery and Characterization of UROD Inhibitors for Cancer Therapy
Discovery and Characterization of UROD Inhibitors for Cancer Therapy
批准号:
266442
负责人:
Liu Fei-Fei
金额:
$33.33万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2015-09-01
中文摘要
我们的研究小组最近发现,阻止癌细胞中的尿卟啉原脱羧酶(UROD)蛋白使它们对放射治疗敏感,放射治疗是最常见的癌症治疗之一。 进一步的研究发现,基因上阻止UROD消除
英文摘要
Our research group recently discovered that stopping the uroporphyrinogen decarboxylase (UROD) protein in cancer cells sensitizes them to radiation therapy, one of the most common cancer treatments. Further work found that genetically stopping UROD elimi
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