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Functional characterization of the Gct1 gene product in a mouse ovarian tumour model: genetics, biology and translation

Functional characterization of the Gct1 gene product in a mouse ovarian tumour model: genetics, biology and translation
小鼠卵巢肿瘤模型中 Gct1 基因产物的功能表征：遗传学、生物学和翻译
批准号：
277283
负责人：
Smith Kerri N
金额：
$3.82万
依托单位：
Memorial University of Newfoundland
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-10-01 至 2015-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=277283&lang=en
关键词：
Bioinformatics Endocrinology Gene Sequencing Genomics Immunohistochemistry Mouse Genetics Next Generation Sequencing Ovarian Cancer Ovarian Physiology Quantitative Rt-Pcr

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中文摘要
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英文摘要
Our understanding of cancer susceptibility genes has been greatly enhanced through the study of families that show genetic heritability for specific cancers. Genes for cancer susceptibility play a particularly important role in the etiology of pediatric
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会议论文
Genetic Polymorphisms Associated with Juvenile-Onset Granulosa Cell Tumour Susceptibility in SWR Mice
Identification of Gct1 using Next Generation sequencing and functional candidate testing in vivo
A candidate gene short list for a granulosa cell tumour susceptibility gene (Gct1) in a spontaneous mouse model of early-onset tumourigenesis
Positional cloning of the Gct1 granulosa cell tumour susceptibility locus in SWR/Bm inbred mice.
  • 批准号：
    200160
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2010
  • 负责人：
    Smith Kerri N
  • 依托单位：
    Memorial University of Newfoundland
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