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Positional cloning of the Gct1 granulosa cell tumour susceptibility locus in SWR/Bm inbred mice.

Positional cloning of the Gct1 granulosa cell tumour susceptibility locus in SWR/Bm inbred mice.
SWR/Bm 近交小鼠中 Gct1 颗粒细胞肿瘤易感位点的定位克隆。
批准号：
200160
负责人：
Smith Kerri N
金额：
$1.27万
依托单位：
Memorial University of Newfoundland
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-02-01 至 2011-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=200160&lang=en
关键词：
Animal Husbandry Animal Surgery Bioinformatics Gene Mapping Genomics Mouse Genetics Ovarian Cancer Ovarian Physiology Quantitative Rt-Pcr Sex-Cord Stromal Tumours

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英文摘要
Juvenile-type granulosa cell tumours, or JGCTs, are a subtype of ovarian cancer that appears before the onset of puberty in girls as young as one year of age. As in other pediatric cancers, the impact of environmental factors on risk is limited, indicatin
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Genetic Polymorphisms Associated with Juvenile-Onset Granulosa Cell Tumour Susceptibility in SWR Mice
Identification of Gct1 using Next Generation sequencing and functional candidate testing in vivo
Functional characterization of the Gct1 gene product in a mouse ovarian tumour model: genetics, biology and translation
  • 批准号：
    277283
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $3.82万
  • 财政年份：
    2012
  • 负责人：
    Smith Kerri N
  • 依托单位：
    Memorial University of Newfoundland
A candidate gene short list for a granulosa cell tumour susceptibility gene (Gct1) in a spontaneous mouse model of early-onset tumourigenesis
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