Flavonol deglycosylation in arabidopsis

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The availability of sequenced genomes and metabolite profiling technologies offer scientists the required tools to investigate secondary metabolism in plants. In plants, flavonoid accumulation is regulated by developmental and environmental stress factors. In many plants, flavonol glycoside conjugates accumulate as major end products and storage pools of flavonoid biosynthesis. Interestingly, the deconjugated flavonol aglycone pool is increased during physiologically determined processes in plants. Although, there are numerous studies describing the genes and enzymes promoting flavonol biosynthesis, very little information exists on the biochemical processes that govern flavonol deglycosylation and turnover. Over the past few decades, there is mounting evidence that glycosyl hydrolases mediate the liberation of bioactive aglycones from glycoside conjugated flavonoids. Arabidopsis thaliana has become a model for flavonoid biochemistry and genetics. We will analyze and describe the mechanisms involved in the conversion of flavonol glycoside to aglycone pools during plant development and environmental stress acclimation.