Theory and Efficient Algorithms for Hard, Large Scale, Numerical Optimization

大规模硬数值优化的理论和高效算法

• 批准号: 9161-2013
• 负责人: Wolkowicz, Henry
• 金额: $ 2.48万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=544597
• 关键词: Theory; Efficient; Algorithms; Hard; Large

The focus of my research will be the proper modelling of hard problems, and the design and implementation of efficient and robust numerical algorithms for large scale, hard, optimization problems. The problems I will deal with arise in many important applications, e.g. molecular conformation (MC), sensor network localization (SNL), inverse imaging and machine learning. In particular, many of these problems arise in the relaxations of hard combinatorial optimization problems. In many instances, the usual modelling approaches result in problems that are both large scale and ill-posed. Therefore, they are hard to solve numerically. Rather than being a disadvantage, one can often take advantage of the ill-posedness to get both a stable problem and one that is smaller in size. In particular, for problems such as SNL one can solve huge problems to high accuracy by exploiting the hidden degeneracy. I plan on applying this technique to MC problems with noisy data as well as to protein design problems.

我的研究重点将是对困难问题进行适当的建模，以及为大规模、困难的优化问题设计和实现高效和健壮的数值算法。我将要处理的问题出现在许多重要的应用中，例如分子构象(MC)、传感器网络定位(SNL)、逆成像和机器学习。特别是，这些问题中的许多都是在困难的组合优化问题的松弛下出现的。在许多情况下，通常的建模方法会导致大规模和不适定的问题。因此，它们很难在数值上求解。与其成为劣势，人们往往可以利用这种不适定性，既得到一个稳定的问题，又得到一个规模较小的问题。特别是，对于像SNL这样的问题，人们可以利用隐藏的简并性来高精度地解决巨大的问题。我计划将这一技术应用于带有噪声数据的MC问题以及蛋白质设计问题。