Development of automated single cell manipulation and analysis techniques for rare cell applications

开发用于稀有细胞应用的自动化单细胞操作和分析技术

• 批准号: 298219-2012
• 负责人: Park, Edward
• 金额: $ 2.26万
• 依托单位: Simon Fraser University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=548266
• 关键词: Development; automated; single; cell; manipulation

The proposed research program will develop novel manipulation and analysis techniques for rare single cells. Single cell analysis is an emerging field that is gaining significant interest in life/health sciences since it can facilitate accurate studies of cellular and molecular behaviours of living cells. This will further our knowledge about cell plasticity, heterogeneity, monitoring infections, auto-immunity, drug delivery, stem cell analysis, or cancer cell detection-all at the single cell level. These applications and other advances in life sciences and health research are driving the need to develop new techniques and tools that can rapidly perform more complex and accurate single cell analysis.

拟议的研究计划将为罕见的单细胞开发新的操作和分析技术。单细胞分析是一个新兴的领域，因为它可以促进对活细胞的细胞和分子行为的准确研究，因此在生命/健康科学中获得了极大的兴趣。这将进一步加深我们对细胞可塑性、异质性、监测感染、自身免疫、药物输送、干细胞分析或癌细胞检测的认识——所有这些都是在单细胞水平上进行的。这些应用以及生命科学和健康研究的其他进展推动了对开发新技术和工具的需求，这些技术和工具可以快速执行更复杂和准确的单细胞分析。