Moving forward in radiation therapy: Dose verification and mapping cellular response

放射治疗的进展：剂量验证和细胞反应图谱

• 批准号: 311877-2010
• 负责人: Jirasek, Andrew
• 金额: $ 0.03万
• 依托单位: University of Victoria
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=548541
• 关键词: Moving; forward; radiation; therapy; Dose

It is estimated that between 40 - 45% of Canadians will develop cancer within their lifetimes and that 1 in 4 Canadians will die from the disease. Cancer remains a significant health-care issue worldwide, outweighing heart disease in potential years of life lost. Approximately one half of all cancer patients will receive some form of radiation therapy (RT). As such, research in RT stands to positively impact the quality of life of a large number of patients. This proposal outlines research in two main areas related to RT of cancer: (i) experimental 3D dose measurement of complex radiation treatments; and (ii) the investigation of new imaging technologies (termed Raman microscopy) as a potential tool for mapping cellular response to RT.

据估计，40% - 45%的加拿大人将在一生中患上癌症，四分之一的加拿大人将死于癌症。癌症仍然是世界范围内一个重要的卫生保健问题，在潜在的寿命损失方面超过了心脏病。大约一半的癌症患者将接受某种形式的放射治疗（RT）。因此，放疗研究将对大量患者的生活质量产生积极影响。本提案概述了与癌症放射治疗相关的两个主要领域的研究：(i)复杂放射治疗的实验性三维剂量测量；（ii）研究新的成像技术（称为拉曼显微镜），作为绘制细胞对RT反应的潜在工具。