Microparticle formation mechanisms in spray drying

喷雾干燥中微粒的形成机制

• 批准号: 387230-2010
• 负责人: Vehring, Reinhard
• 金额: $ 2.19万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=550604
• 关键词: Microparticle; formation; mechanisms; spray; drying

Structured microparticles are the basis for a new class of therapeutics for respiratory diseases. Respiratory infections and chronic pulmonary conditions account for the highest mortality world-wide and cause large financial strain on health-care systems. Therapeutics based on advanced microparticles can be delivered to the lung more efficiently and less expensively. These microparticles can also stabilize the drugs against environmental stress and high storage temperatures such that world-wide distribution of respiratory therapeutics and vaccines may become feasible.

结构微粒是一种新型呼吸系统疾病疗法的基础。呼吸道感染和慢性肺病是世界范围内死亡率最高的疾病，并对卫生保健系统造成巨大的财政压力。基于先进微粒的治疗方法可以更有效、更便宜地输送到肺部。这些微粒还可以稳定药物，使其不受环境压力和高储存温度的影响，从而使呼吸疗法和疫苗在世界范围内的分销成为可能。