Benchmark proprietary pyridine- and thienopyrimidine-based bisphosphonates against the standard of care drug Zometa® in the treatment of multiple myeloma
Benchmark proprietary pyridine- and thienopyrimidine-based bisphosphonates against the standard of care drug Zometa® in the treatment of multiple myeloma
将基于吡啶和噻吩并嘧啶的专利双膦酸盐与治疗多发性骨髓瘤的护理药物 Zometa® 标准进行基准比较
批准号：
293953
负责人：
Tsantrizos Youla S
金额：
$11.66万
依托单位：
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-09-01 至 2014-09-01
中文摘要
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英文摘要
The enzyme farnesyl pyrophosphate synthase (hFPPS) is responsible for the production of farnesyl pyrophosphate (FPP), a human metabolite that plays a major role in biochemical processes associated with cancer. Multiple myeloma is a cancer of the white bl
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Molecular Tools that Block Maturation of the Nuclear Lamin A, Leading to Decrease in Proliferation and Metastasis of Pancreatic Ductal Adenocarcinoma and Colorectal Cancer
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批准号：461368
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项目类别：Operating Grants
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资助金额：$78.02万
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财政年份：2022
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负责人：Tsantrizos Youla S
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依托单位：
Validation of the human geranylgeranyl pyrophosphate synthase (hGGPPS) as a therapeutic target for cancer chemotherapy and design of pre-clinical candidates for the treatment of multiple myeloma
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批准号：380326
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项目类别：Operating Grants
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资助金额：$64.34万
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财政年份：2018
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负责人：Tsantrizos Youla S
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依托单位：
Validation of the human farnesyl pyrophosphate synthase (hFPPS) as a therapeutic target and design of pre-clinical candidates for the treatment of multiple myeloma and neurodegenerative diseases.
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批准号：265657
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项目类别：Operating Grants
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资助金额：$51.28万
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财政年份：2012
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负责人：Tsantrizos Youla S
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依托单位：
海外基金
