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Molecular Tools that Block Maturation of the Nuclear Lamin A, Leading to Decrease in Proliferation and Metastasis of Pancreatic Ductal Adenocarcinoma and Colorectal Cancer

Molecular Tools that Block Maturation of the Nuclear Lamin A, Leading to Decrease in Proliferation and Metastasis of Pancreatic Ductal Adenocarcinoma and Colorectal Cancer
阻止核纤层蛋白 A 成熟的分子工具,可减少胰腺导管腺癌和结直肠癌的增殖和转移
批准号:
461368
负责人:
Tsantrizos Youla S
金额:
$78.02万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01

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The number of new cancer cases in Canada continues to increase annually, (in part) due to our growing aging population. The Canadian Cancer Society estimated that between 2015 and 2030, new cases of cancer would increase by approximately 40%. There is an
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Validation of the human geranylgeranyl pyrophosphate synthase (hGGPPS) as a therapeutic target for cancer chemotherapy and design of pre-clinical candidates for the treatment of multiple myeloma
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    380326
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  • 资助金额:
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  • 财政年份:
    2018
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Benchmark proprietary pyridine- and thienopyrimidine-based bisphosphonates against the standard of care drug Zometa® in the treatment of multiple myeloma
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    293953
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  • 财政年份:
    2013
  • 负责人:
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Validation of the human farnesyl pyrophosphate synthase (hFPPS) as a therapeutic target and design of pre-clinical candidates for the treatment of multiple myeloma and neurodegenerative diseases.
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    265657
  • 项目类别:
    Operating Grants
  • 资助金额:
    $51.28万
  • 财政年份:
    2012
  • 负责人:
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