Validation of the human farnesyl pyrophosphate synthase (hFPPS) as a therapeutic target and design of pre-clinical candidates for the treatment of multiple myeloma and neurodegenerative diseases.
Validation of the human farnesyl pyrophosphate synthase (hFPPS) as a therapeutic target and design of pre-clinical candidates for the treatment of multiple myeloma and neurodegenerative diseases.
验证人法呢基焦磷酸合酶 (hFPPS) 作为治疗靶点，并设计用于治疗多发性骨髓瘤和神经退行性疾病的临床前候选药物。
批准号：
265657
负责人：
Tsantrizos Youla S
金额：
$51.28万
依托单位：
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-09-01 至 2017-09-01
中文摘要
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英文摘要
The enzyme farnesyl pyrophosphate synthase (hFPPS) is responsible for the biosynthesis of farnesyl pyrophosphate (FPP), a key metabolite in the biochemistry and physiology of the human body. Abnormally high activity of hFPPS has been implicated in numero
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财政年份：2022
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负责人：Tsantrizos Youla S
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依托单位：
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财政年份：2018
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负责人：Tsantrizos Youla S
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依托单位：
Benchmark proprietary pyridine- and thienopyrimidine-based bisphosphonates against the standard of care drug Zometa® in the treatment of multiple myeloma
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批准号：293953
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项目类别：Operating Grants
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资助金额：$11.66万
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财政年份：2013
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负责人：Tsantrizos Youla S
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依托单位：
海外基金
