The role of Toll-like receptor 4 as an upstream modulator of poor outcome in experimental subarachnoid hemorrhage.

Toll 样受体 4 作为实验性蛛网膜下腔出血不良结果上游调节剂的作用。

• 批准号: 331381
• 负责人: Brathwaite Shakira
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-12-01 至 2015-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=331381&lang=en
• 关键词: Delayed Cerebral Ischemia (Dci); Inflammation; Microglia; Subarachnoid Hemorrhage (Sah); Toll-Like Receptor 4 (Tlr4); Tumor Necrosis Factor Alpha (Tnfa)

Subarachnoid hemorrhage (SAH) only comprises 7% of stroke cases worldwide, yet due to its relatively early age of onset and poor outcome, its socioeconomic impact rivals that of ischemic stroke, the most common stroke variant. Poor outcome is largely attr

蛛网膜下腔出血（SAH）仅占全球卒中病例的7%，但由于其相对较早的发病年龄和不良结局，其社会经济影响可与缺血性卒中（最常见的卒中变体）相媲美。结果不佳主要是由于