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Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone

Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone
共同靶向甲状旁腺激素相关蛋白（PTHrP）信号传导和破骨细胞激活以对抗乳腺癌骨转移
批准号：
321112
负责人：
Kremer Richard B
金额：
$53.91万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=321112&lang=en
关键词：
Bone Breast Cancer Cancer Stem Cells Metastasis Neoplasia Pthrp Pymt-Mmtv Mice Triple-Negative Breast Cancer

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英文摘要
Skeletal metastases appear as complications in up to 70% of breast cancer patients. Once bone tumors are established, they are usually incurable. In advanced cases, the skeleton often bears the major tumor burden, causing considerable suffering and morbid
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  • 批准号：
    280255
  • 项目类别：
    Operating Grants
  • 资助金额：
    $50.07万
  • 财政年份：
    2013
  • 负责人：
    Kremer Richard B
  • 依托单位：
    McGill University
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