Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone
共同靶向甲状旁腺激素相关蛋白(PTHrP)信号传导和破骨细胞激活以对抗乳腺癌骨转移
基本信息
- 批准号:321112
- 负责人:
- 金额:$ 53.91万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2015
- 资助国家:加拿大
- 起止时间:2015-03-01 至 2020-03-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Skeletal metastases appear as complications in up to 70% of breast cancer patients. Once bone tumors are established, they are usually incurable. In advanced cases, the skeleton often bears the major tumor burden, causing considerable suffering and morbid
高达70%的乳腺癌患者出现骨转移并发症。骨肿瘤一旦形成,通常无法治愈。在晚期病例中,骨骼通常承担主要肿瘤负担,造成相当大的痛苦和病态。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Kremer Richard B其他文献
Kremer Richard B的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Kremer Richard B', 18)}}的其他基金
Anti-parathyroid hormone-related protein (PTHrP) monoclonal antibodies against metastatic cancer
抗转移性癌症的抗甲状旁腺激素相关蛋白 (PTHrP) 单克隆抗体
- 批准号:
470394 - 财政年份:2022
- 资助金额:
$ 53.91万 - 项目类别:
Operating Grants
Co-targeting parathyroid hormone-related protein (PTHrP) and osteoclast activation to counter breast cancer metastasis to bone.
共同靶向甲状旁腺激素相关蛋白 (PTHrP) 和破骨细胞激活,以对抗乳腺癌骨转移。
- 批准号:
470441 - 财政年份:2022
- 资助金额:
$ 53.91万 - 项目类别:
Operating Grants
Effect of 1,25 dihydroxyvitamin D on control of cell growth and differentiation
1,25 二羟基维生素 D 对细胞生长和分化控制的影响
- 批准号:
390863 - 财政年份:2018
- 资助金额:
$ 53.91万 - 项目类别:
Operating Grants
Effect of 1,25 dihydroxyvitamin D on control of cell growth and differentiation
1,25 二羟基维生素 D 对细胞生长和分化控制的影响
- 批准号:
280255 - 财政年份:2013
- 资助金额:
$ 53.91万 - 项目类别:
Operating Grants
Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone
共同靶向甲状旁腺激素相关蛋白(PTHrP)信号传导和破骨细胞激活以对抗乳腺癌骨转移
- 批准号:
189509 - 财政年份:2009
- 资助金额:
$ 53.91万 - 项目类别:
Operating Grants
Effect of 1,25 dihydroxyvitamin D on control of cell growth and differentiation
1,25 二羟基维生素 D 对细胞生长和分化控制的影响
- 批准号:
172038 - 财政年份:2008
- 资助金额:
$ 53.91万 - 项目类别:
Operating Grants
相似海外基金
Targeting triple-negative breast cancer stem cells and simultaneously boosting anti-tumor immunity.
靶向三阴性乳腺癌干细胞,同时增强抗肿瘤免疫力。
- 批准号:
476301 - 财政年份:2022
- 资助金额:
$ 53.91万 - 项目类别:
Studentship Programs
Altered Lipid Metabolism in Luminal Breast Cancer Stem Cells and Endocrine Resistance
腔内乳腺癌干细胞脂质代谢的改变和内分泌抵抗
- 批准号:
10459264 - 财政年份:2021
- 资助金额:
$ 53.91万 - 项目类别:
Catalyst Award: "Characterization of p27Kip1 as an Enhancer of Stem-Like Properties in Breast Cancer Stem Cells"
催化剂奖:“p27Kip1 作为乳腺癌干细胞干细胞样特性增强剂的表征”
- 批准号:
2100655 - 财政年份:2021
- 资助金额:
$ 53.91万 - 项目类别:
Standard Grant
RNA regulator in breast cancer stem cells and its application to therapy
乳腺癌干细胞中的RNA调节因子及其在治疗中的应用
- 批准号:
21K19403 - 财政年份:2021
- 资助金额:
$ 53.91万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Establishment of a new personalized drug selection system based on drug sensitivity of breast cancer stem cells
基于乳腺癌干细胞药物敏感性建立新型个性化药物选择体系
- 批准号:
20K08981 - 财政年份:2020
- 资助金额:
$ 53.91万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
New method for predicting the effect of drug therapy by quantifying breast cancer stem cells and regulatory T cells
通过量化乳腺癌干细胞和调节性T细胞来预测药物治疗效果的新方法
- 批准号:
19K18055 - 财政年份:2019
- 资助金额:
$ 53.91万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Analysis of mechanisms in which upregulation of MCM10 contributes to maintenance of breast cancer stem cells
MCM10上调有助于维持乳腺癌干细胞的机制分析
- 批准号:
19K23910 - 财政年份:2019
- 资助金额:
$ 53.91万 - 项目类别:
Grant-in-Aid for Research Activity Start-up














{{item.name}}会员




