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Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone

Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone
共同靶向甲状旁腺激素相关蛋白（PTHrP）信号传导和破骨细胞激活以对抗乳腺癌骨转移
批准号：
189509
负责人：
Kremer Richard B
金额：
$36.88万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-09-01 至 2013-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=189509&lang=en
关键词：
Bone Metastases Breast Cancer Co-Targeted Therapy Neutralising Antibody Pthrp

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中文摘要
翻译
骨转移是乳腺癌进展的灾难性后果，高达70%的乳腺癌患者死于骨转移。由于高血钙、病理性骨折和骨内瘤，骨转移引起相当大的痛苦
英文摘要
Bone metastases are catastrophic consequences of breast cancer progression and are present in up to 70% of patients who die from breast cancer. Skeletal metastases cause considerable suffering due to high serum calcium, pathological fractures and intracta
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Anti-parathyroid hormone-related protein (PTHrP) monoclonal antibodies against metastatic cancer
Co-targeting parathyroid hormone-related protein (PTHrP) and osteoclast activation to counter breast cancer metastasis to bone.
Effect of 1,25 dihydroxyvitamin D on control of cell growth and differentiation
Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone
  • 批准号：
    321112
  • 项目类别：
    Operating Grants
  • 资助金额：
    $53.91万
  • 财政年份：
    2015
  • 负责人：
    Kremer Richard B
  • 依托单位：
    McGill University
海外基金