Advanced tools for bed bug pest management

臭虫是人类的专职吸血动物。近年来，包括加拿大和美国在内的许多国家的臭虫危害急剧增加，导致人们对设计更好的管理工具和控制方案重新产生了兴趣。根据加拿大卫生部的说法，从无家可归者收容所到五星级酒店，甚至在公共交通工具上，它们现在随处可见。鉴于臭虫是最难根除的害虫之一，因为它们体型小，对常规杀虫剂表现出抗药性，而且易于运输，因此拟议研究的主要目标是促进管理臭虫的产品的开发，臭虫是一种重新出现的公共卫生有害生物，基于一、信息化学品--无毒行为调节物质，以及二。天然产物，如硅藻土(DE)和植物性杀虫剂。 这项建议的总体目标是开发一种室内害虫管理系统，以防治常见的臭虫Cimex lectularius，其基础是：a.改变行为的合成信息素类似物作为个人保护的驱避剂和诱捕剂用于诱捕和监测；b.驱避剂或引诱剂的二元混合物的协同作用；c.增强的DE对臭虫的致死作用；D.DE和引诱剂的混合物=“吸引并杀死”策略；E.DE和豌豆提取物/豌豆蛋白或其他天然材料的混合物，以提高DE的效力。几乎没有无毒的管理工具可以用来减轻臭虫。开发这种工具不仅对两家年轻的温哥华公司(SemioBIO Technologies，DE实验室)有利，而且随着这种害虫在世界各地死灰复燃，在全球范围内具有潜在的社会经济价值。

Bed bugs are obligate blood feeders on humans. In recent years, bed bug infestations have increased dramatically in many countries including Canada and USA, leading to a renewed interest in designing better management tools and control options. According to Health Canada they can now be found everywhere from homeless shelters to five-star hotels, and even on public transportation. Given that bed bugs are among the most difficult pests to eradicate due to their small size, demonstrated resistance to conventional insecticides and their ease of transport, the key objective of the proposed research is to facilitate the development of products for management of bed bugs, a re-emerged public health pest, based on i. semiochemicals - non-toxic behaviour-modifying substances, and ii. natural products such as diatomaceous earth (DE) and botanical insecticides. The overall goals of this proposal are to develop an indoor pest management system against the common bed bug, Cimex lectularius based on: a. behavior-modifying synthetic pheromone analogs as repellents for personal protection and attractants for trapping and monitoring; b. synergistic effects of binary mixtures of repellents or attractants; c. enhanced DE for lethal effects against bed bugs; d. mixtures of DE and attractants = "attract and kill" strategy; e. mixtures of DE and pea extract/pea protein or other natural materials to increase the efficacy of DE. There are few non-toxic management tools available to mitigate bed bugs. Development of such tools would not only be beneficial to two young Vancouver companies (SemioBIO Technologies, DE Laboratories), but of potential socio-economic value globally as resurgence of this pest has occurred worldwide.